DMF
DMF: The Ultimate Solution for Pharmaceutical and Industrial Applications
DMF (Dimethyl Formamide) is a versatile organic compound widely used in pharmaceutical manufacturing, chemical synthesis, and industrial applications. With our high-purity DMF products, we provide reliable solutions for various industries requiring superior solvent performance.
Key Product Specifications:
- Chemical Formula: C3H7NO
- Molecular Weight: 73.09 g/mol
- Appearance: Clear, colorless liquid
- Purity: ≥99.9% (HPLC Grade available)
- Boiling Point: 153°C (307°F)
- Melting Point: -61°C (-78°F)
- Density: 0.944 g/mL at 25°C
- Vapor Pressure: 3.7 mmHg at 25°C
| Grade | Purity | Water Content | Acidity (as HCOOH) | Applications |
|---|---|---|---|---|
| Industrial | ≥99.5% | ≤0.1% | ≤0.05% | Paints, coatings, adhesives |
| Pharmaceutical | ≥99.8% | ≤0.05% | ≤0.02% | API synthesis, drug formulation |
| HPLC | ≥99.9% | ≤0.02% | ≤0.01% | Analytical chromatography |
Packaging Options:
- 200L steel drums (net weight: 170kg)
- 1000L IBC containers (net weight: 850kg)
- ISO tank containers (20,000L capacity)
- Custom packaging available upon request
DMF Applications in Various Industries:
DMF serves as an excellent polar aprotic solvent with numerous applications:
- Pharmaceutical industry: Solvent for APIs, reaction medium
- Chemical synthesis: For polyurethane, acrylic fibers, and resins
- Electronics: Semiconductor cleaning and processing
- Petrochemical: Gas absorption and purification
- Paints & Coatings: Formulating high-performance coatings
DMF FAQ Section 1
Q: What safety precautions should be taken when handling DMF?
A: DMF requires careful handling due to its toxicity and flammability. Always use appropriate PPE including chemical-resistant gloves, goggles, and protective clothing. Ensure adequate ventilation and avoid inhaling vapors. In case of skin contact, wash immediately with plenty of water. Store in tightly closed containers away from heat sources and oxidizing agents.
Q: How should DMF be stored to maintain quality?
A: DMF should be stored in sealed containers made of stainless steel, aluminum, or polyethylene. Keep in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Optimal storage temperature is between 15-25°C. Under proper conditions, DMF can maintain its quality for up to 2 years from production date.
Technical Performance Data
| Parameter | Value | Test Method |
|---|---|---|
| Refractive Index (n20/D) | 1.4305 - 1.4325 | ASTM D1218 |
| Dielectric Constant (20°C) | 36.71 | ASTM D150 |
| Viscosity (25°C) | 0.802 mPa·s | ASTM D445 |
| Flash Point (closed cup) | 58°C (136°F) | ASTM D93 |
| Autoignition Temperature | 445°C (833°F) | ASTM E659 |
DMF FAQ Section 2
Q: What are the main differences between pharmaceutical and industrial grade DMF?
A: Pharmaceutical grade DMF undergoes additional purification steps to achieve higher purity (≥99.8%) and lower impurity levels, especially for water content, acidity, and non-volatile residues. It's manufactured under strict GMP conditions with complete traceability. Industrial grade DMF (≥99.5% purity) is suitable for less sensitive applications and typically has slightly higher tolerance for certain impurities.
Q: Can DMF be mixed with water and other solvents?
A: DMF is completely miscible with water and most organic solvents including alcohols, ethers, esters, and aromatic hydrocarbons. However, mixing ratios should be carefully considered as they can affect solution properties. With water, DMF forms an azeotrope (35.5% water) that boils at 99.4°C. Solvent mixtures containing DMF should be evaluated for specific applications.
Regulatory Information
Our DMF products comply with international standards and regulations:
- REACH registered
- USP/NF, Ph. Eur. compliant (for pharmaceutical grade)
- Meets FDA requirements for indirect food contact applications
- Certificates of Analysis available for all batches
DMF FAQ Section 3
Q: What are the environmental considerations for DMF disposal?
A: DMF should never be disposed of in drains or waterways. As a hazardous waste, it must be collected for professional disposal according to local regulations. Small quantities can be absorbed with inert material (vermiculite, sand) and disposed as hazardous waste. Large quantities require specialized waste management services. Consider recycling options as DMF can often be purified and reused.
Q: How does temperature affect DMF performance?
A: Temperature significantly impacts DMF properties. Higher temperatures increase volatility and decrease viscosity, enhancing mass transfer in reactions. However, elevated temperatures may accelerate decomposition (especially above 60°C). Below 20°C, viscosity increases slightly. For precise applications, temperature control is recommended as DMF's dielectric constant and solvent power vary with temperature.
Shipping and Handling Guidelines
- UN Number: UN2265
- Proper Shipping Name: N,N-DIMETHYLFORMAMIDE
- Hazard Class: 3 (Flammable liquid)
- Packing Group: III
- Marine Pollutant: Yes
- Special precautions required for air transportation
Custom Solutions Available
We offer customized DMF formulations for specific applications:
- Stabilized grades with extended shelf life
- Low-water content versions for moisture-sensitive applications
- Special packaging with inert gas blanket
- Blended solvent systems incorporating DMF